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Alectinib - Roche

Drug Profile

Alectinib - Roche

Alternative Names: AF-802; Alecensa; ALECENSARO; Alectinib hydrochloride; CH-5424802; RG-7853; RO-5424802; RO-5452802

Latest Information Update: 12 Jun 2024

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At a glance

  • Originator Chugai Pharmaceutical
  • Developer Chugai Pharmaceutical; National Hospital Organization Nagoya Medical Center; Roche; Seoul National University Hospital; University College London
  • Class Antineoplastics; Carbazoles; Morpholines; Nitriles; Phenyl ethers; Piperidines; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Non-small cell lung cancer; Anaplastic large cell lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Non-small cell lung cancer
  • Registered Anaplastic large cell lymphoma
  • Phase II Solid tumours
  • Phase I/II Brain cancer; Thyroid cancer

Most Recent Events

  • 10 Jun 2024 Registered for Non-small cell lung cancer (Adjuvant therapy) in Liechtenstein, Iceland, Norway, European Union (PO)
  • 18 Apr 2024 Registered for Non-small cell lung cancer (Adjuvant therapy, First-line therapy) in USA (PO)
  • 27 Feb 2024 Genentech completes a phase II trial in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (PO) (NCT04632992)
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