Research programme: neurodegenerative disease therapeutics - ProMIS Neurosciences

Drug Profile

Research programme: neurodegenerative disease therapeutics - ProMIS Neurosciences

Alternative Names: huPMN310; PMN 300; PMN 320; PMN 330; PMN 340; PMN 350; PMN-310; TDP 43 targeting therapeutics

Latest Information Update: 03 Jul 2018

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At a glance

  • Originator Amorfix Life Sciences
  • Developer ProMIS Neurosciences
  • Class Antidementias; Antiparkinsonians; Monoclonal antibodies; Neuroprotectants
  • Mechanism of Action Alpha-synuclein modulators; Amyloid beta-protein modulators; Superoxide dismutase inhibitors; Tau protein inhibitors; TDP-43 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Amyotrophic lateral sclerosis; Parkinson's disease

Highest Development Phases

  • Preclinical Alzheimer's disease; Amyotrophic lateral sclerosis; Dementia
  • Research Down syndrome; Lewy body disease; Parkinson's disease

Most Recent Events

  • 03 Jul 2018 Preclinical development is ongoing in Amyotrophic-lateral-sclerosis in Canada (Parenteral) (ProMIS Neurosciences Pipeline; 9244075)
  • 26 Jun 2018 Research programme: neurodegenerative disease therapeutics - ProMIS Neurosciences is available for licensing as of 26 Jun 2018.
  • 12 Jun 2018 ProMIS Neurosciences plans a phase I trial of PMN 310 for Alzheimer's disease, in the second half of 2019
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