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Human retinal pigment epithelial cell therapy - Astellas Pharma

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Drug Profile

Human retinal pigment epithelial cell therapy - Astellas Pharma

Alternative Names: ACT hESC-RPE; ASP-7317; CHAPhoR 201-AMD; hESC-derived RPE; hRPE cell therapy; Human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells - Astellas; MA09-hRPE

Latest Information Update: 15 Feb 2024

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At a glance

  • Originator Advanced Cell Technology
  • Developer Astellas Institute for Regenerative Medicine; Astellas Pharma
  • Class Eye disorder therapies; Pluripotent stem cell therapies; Stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Stargardt disease
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Age-related macular degeneration; Macular degeneration
  • Research Stargardt disease
  • No development reported Degenerative myopia

Most Recent Events

  • 08 Feb 2024 CHA Bio terminates a phase I/IIa trial for Age-related macular degeneration in South Korea due to sponsors decision (NCT01674829)
  • 31 Jul 2023 Early research in Stargardt disease in Japan (Intraocular) (Astellas Pharma pipeline, August 2023)
  • 28 Jul 2018 No recent reports of development identified for preclinical development in Degenerative myopia in USA (Intraocular, Injection)

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