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Vesatolimod - Gilead Sciences

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Drug Profile

Vesatolimod - Gilead Sciences

Alternative Names: GS-9620

Latest Information Update: 09 May 2025

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At a glance

  • Originator Gilead Sciences
  • Developer Aelix Therapeutics; Gilead Sciences; National Institute of Allergy and Infectious Diseases
  • Class Amines; Antiretrovirals; Antivirals; Ethers; Pteridines; Pyrrolidines; Small molecules
  • Mechanism of Action Toll-like receptor 7 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections
  • Discontinued Hepatitis B; Hepatitis C

Most Recent Events

  • 25 Apr 2025 National Institute of Allergy and Infectious Diseases in collaboration with Gilead Sciences suspends a phase I/II trial in HIV 1 infection (Combination therapy,Treatment-experienced) in US and Brazil (NCT06071767)
  • 12 Mar 2025 Adverse events data from a phase IIa trial in HIV 1 infections released by Gilead Sciences
  • 16 Jan 2025 Gilead Sciences completes phase II FRESH trial in HIV-1 infections in South Africa (IV) (NCT05281510)

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