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Vesatolimod - Gilead Sciences

Drug Profile

Vesatolimod - Gilead Sciences

Alternative Names: GS-9620

Latest Information Update: 12 Apr 2024

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At a glance

  • Originator Gilead Sciences
  • Developer Aelix Therapeutics; Gilead Sciences
  • Class Amines; Antiretrovirals; Antivirals; Ethers; Pteridines; Pyrrolidines; Small molecules
  • Mechanism of Action Toll-like receptor 7 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections
  • Discontinued Hepatitis B; Hepatitis C

Most Recent Events

  • 01 Apr 2024 Phase-I/II clinical trials in HIV-1 infections (Combination therapy, Treatment-experienced) in USA (PO) (NCT06071767)
  • 03 Mar 2024 Immunogenicity data from phase I trial in HIV-1 infections were presented at the 31st Conference on Retroviruses and Opportunistic Infections (CROI-2024)
  • 27 Nov 2023 Gilead Sciences terminates phase I trial in HIV-1 infections in the USA (PO) due to sponsor's decision to change the clinical development plan of this molecule (NCT05458102)
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