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Arbaclofen - Seaside Therapeutics

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Drug Profile

Arbaclofen - Seaside Therapeutics

Alternative Names: R-baclofen; STX-209

Latest Information Update: 28 May 2025

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At a glance

  • Originator Seaside Therapeutics
  • Developer Seaside Therapeutics; The Childrens Hospital of Philadelphia; UMC
  • Class Aminobutyric acids; Behavioural disorder therapies; Gastrokinetics; Muscle relaxants; Small molecules
  • Mechanism of Action GABA B receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Fragile X syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Fragile X syndrome
  • Phase II Autism spectrum disorder

Most Recent Events

  • 28 May 2025 No recent reports of development identified for phase-0 development in Autism spectrum disorder (In adolescents) in USA (PO, Fast dissolve)
  • 18 Sep 2023 Allos Pharma has patent protection for arbaclofen in USA
  • 18 Sep 2023 Allos Pharma plans a confirmatory phase III trial in Fragile X syndrome

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