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BTRX 246040

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Drug Profile

BTRX 246040

Alternative Names: BTRX-246040; LY 2940094

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Eli Lilly
  • Developer BlackThorn Therapeutics; Eli Lilly
  • Class Antidepressants; Antiparkinsonians; Drug withdrawal therapies; Small molecules
  • Mechanism of Action Nociceptin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Major depressive disorder
  • Preclinical Parkinson's disease
  • Discontinued Alcoholism

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 12 Dec 2017 9228737: Updated KDM, added PD and TT data, made neurological disorder line dormant as it is broad indication and details of specific dev lines are available. Creatd FET. Created relevant HEs. Sent THES request to map Antiparkionsonians as DC. Did not complete earlier FET as it talks about series of pII trials.
  • 07 Dec 2017 BlackThorn Therapeutics plans to initiate a phase IIa trial Parkinson’s disease in 2018
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