MEDI 565

Drug Profile

MEDI 565

Alternative Names: AMG-211; CEA BiTE mAb; MEDI-565; MT-111

Latest Information Update: 25 Jan 2018

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At a glance

  • Originator Micromet Inc
  • Developer Amgen; MedImmune; University Medical Center Groningen
  • Class Antineoplastics; Bispecific antibodies
  • Mechanism of Action Carcinoembryonic antigen inhibitors; CD3 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Gastrointestinal cancer

Most Recent Events

  • 09 Jan 2018 Amgen completes a phase I trial in Gastrointestinal cancer (Late-stage disease, Second-line therapy or greater) in Germany and Netherlands (IV) (NCT02291614)
  • 20 Jun 2016 Phase-I/II clinical trials in Gastrointestinal cancer (Late-stage disease, Second-line therapy or greater) in Netherlands (IV) (EudraCT2015-004370-14)
  • 01 Jan 2015 MedImmune and Micromet complete a phase I trial in Gastrointestinal cancer (Late-stage disease) in USA (NCT01284231)
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