Research programme: cancer therapies - H3 Biomedicine

Drug Profile

Research programme: cancer therapies - H3 Biomedicine

Alternative Names: SF3B1 inhibitors - H3 Biomedicine; SF3B1 modulator - H3 Biomedicine; Splicing factor inhibitor - H3 Biomedicine; Splicing inhibitors - H3 Biomedicine

Latest Information Update: 27 Jul 2017

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At a glance

  • Originator H3 Biomedicine
  • Developer H3 Biomedicine; University of British Columbia; Vancouver Coastal Health
  • Class Antineoplastics
  • Mechanism of Action Estrogen receptor antagonists; Phosphoprotein modulators; RNA interference; Type 4 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 08 Jan 2018 H3 Biomedicine announces intention to submit IND application for Cancer in 2019
  • 24 Jul 2017 Preclinical trials in Cancer in Canada (PO)
  • 24 Jul 2017 Pharmacodynamics data from a preclinical trial in Bladder cancer released by H3 Biomedicine
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