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Azemiglitazone - Metabolic Solutions Development Company

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Drug Profile

Azemiglitazone - Metabolic Solutions Development Company

Alternative Names: CIR-0602K; MSDC-0602; MSDC-0602 potassium; MSDC-0602K

Latest Information Update: 15 Dec 2025

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At a glance

  • Originator Metabolic Solutions Development Company
  • Developer Cirius Therapeutics; Metabolic Solutions Development Company
  • Class Antihyperglycaemics; Hepatoprotectants; Insulin sensitisers; Obesity therapies; Small molecules; Thiazolidinediones; Urologics
  • Mechanism of Action Mitochondrial membrane transport protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-alcoholic steatohepatitis
  • Preclinical Obesity
  • Suspended Type 2 diabetes mellitus
  • No development reported Polycystic kidney disease

Most Recent Events

  • 09 Dec 2025 Cirius Therapeutics in collaboration with University of Virginia plans a phase IIa trial for Type I diabetes mellitus in USA (PO) in fourth quarter of 2025 (NCT07186660)
  • 04 Nov 2025 Pharmacodynamics data from a preclinical trial in Obesity released by Cirius Therapeutics
  • 25 Jun 2025 Pharmacodynamics data from a preclinical trial in Obesity released by Cirius Therapeutics

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