Satralizumab - Chugai Pharmaceuticals/Roche
Alternative Names: ENSPRYNG; RG-6168; SA-237; Satralizumab-mwgeLatest Information Update: 13 Jun 2024
At a glance
- Originator Chugai Pharmaceutical
- Developer Chugai Pharmaceutical; Roche
- Class Anti-inflammatories; Antirheumatics; Eye disorder therapies; Monoclonal antibodies
- Mechanism of Action Interleukin 6 receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Neuromyelitis optica
- Phase III Encephalitis; Graves ophthalmopathy
- No development reported Rheumatoid arthritis
- Discontinued Myasthenia gravis
Most Recent Events
- 10 Jun 2024 Hoffmann-La Roche plans to initiate a phase II (SHIELD DMD) trial for Duchenne Muscular Dystrophy (In children, In Adolescents) in the US (SC) (NCT06450639)
- 28 May 2024 Hoffmann-La Roche completes the phase III SAkuraMoon trial in Neuromyelitis optica (Montherpay, Combination therapy, In adolescents, In the elderly, In adults) in USA, Ukraine, Turkey, Taiwan, Spain, South Korea, Romania, Puerto Rico, Malaysia, Japan, Croatia, Canada, Italy (SC, Injection) (NCT04660539) (EudraCT2020-003413-35)
- 09 May 2024 Discontinued - Phase-III for Myasthenia gravis (In adolescents, In the elderly, In adults) in Argentina, Australia, Brazil, China, Canada, France, Germany, Italy, Japan, South Korea, Poland, Russia, Spain, Turkey, Taiwan, USA, Netherlands, Denmark (SC) (Roche pipeline, May 2024)