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Fipaxalparant - Horizon Therapeutics

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Drug Profile

Fipaxalparant - Horizon Therapeutics

Alternative Names: CZN-001; HZN-825; SAR-100842

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator sanofi-aventis
  • Developer Horizon Pharmaceuticals
  • Class Amides; Antifibrotics; Benzene derivatives; Carboxylic acids; Ethers; Indenes; Skin disorder therapies; Small molecules
  • Mechanism of Action Lysophosphatidic acid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diffuse scleroderma; Idiopathic pulmonary fibrosis

Most Recent Events

  • 12 Oct 2023 Chemical structure information added
  • 10 Sep 2023 Pharmacokinetics and adverse event data from a phase I trial in healthy volunteers presented at the American College of Clinical Pharmacology Annual Meeting (ACCP-2023)
  • 10 Sep 2023 Pharmacokinetics data from a phase I trial presented at the American College of Clinical Pharmacology Annual Meeting (ACCP-2023)

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