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Methylthioninium chloride - Provepharm

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Drug Profile

Methylthioninium chloride - Provepharm

Alternative Names: Methylene blue injection - Provepharm; Methylene-blue-Provepharm; Methylthioninium Chloride Hydrate; ProvayBlue; Proveblue

Latest Information Update: 22 Jul 2022

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At a glance

  • Originator Provepharm
  • Developer Daiichi Sankyo Company; Provepharm
  • Class Anti-infectives; Antimalarials; Antivirals; Phenothiazines; Small molecules
  • Mechanism of Action Monoamine oxidase inhibitors; Synuclein inhibitors; Tau protein inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Haemoglobinopathies
  • No development reported Malaria; Septic shock; Viral infections

Most Recent Events

  • 22 Jul 2022 No development reported - Phase-II for Septic shock in USA (IV)
  • 30 Jun 2022 Methylthioninium chloride licensed to American Regent in USA
  • 01 Dec 2019 Phase-II clinical trials in Septic shock in USA (IV) (NCT04089072)

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