Enoblituzumab - MacroGenics

Drug Profile

Enoblituzumab - MacroGenics

Alternative Names: MGA-271

Latest Information Update: 16 May 2018

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At a glance

  • Originator MacroGenics
  • Developer MacroGenics; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CD276 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Prostate cancer
  • Phase I Malignant melanoma; Non-small cell lung cancer; Solid tumours; Squamous cell cancer; Urogenital cancer

Most Recent Events

  • 07 May 2018 MacroGenics completes enrolment in its phase I trial for Melanoma, Head and neck Cancer, Non small cell lung cancer and Urogenital cancer in USA (NCT02475213)
  • 15 Dec 2016 Biomarkers information updated
  • 01 Dec 2016 Phase-I clinical trials in Solid tumours (In adolescents, In children, In infants, In adults, Second-line therapy or greater) in USA (IV) (NCT02982941)
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