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Cenerimod - Idorsia Pharmaceuticals

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Drug Profile

Cenerimod - Idorsia Pharmaceuticals

Alternative Names: ACT-334441; Second selective S1P1 receptor agonist - Idorsia

Latest Information Update: 29 Jan 2026

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At a glance

  • Originator Actelion Pharmaceuticals
  • Developer Idorsia Pharmaceuticals; Viatris
  • Class Antirheumatics; Oxadiazoles; Pyridines; Small molecules
  • Mechanism of Action Sphingosine 1 phosphate receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Lupus nephritis; Systemic lupus erythematosus
  • Preclinical Rheumatoid arthritis
  • No development reported Autoimmune disorders

Most Recent Events

  • 12 Dec 2025 Phase-II clinical trials in Systemic lupus erythematosus (Adjunctive treatment) in China (PO) (NCT07266090)
  • 05 Dec 2025 Viatris Pharmaceuticals plans a phase II trial for Systemic lupus erythematosus (Treatment-experienced) (PO, Tablet) in November 2025 (NCT07266090)
  • 07 Nov 2025 Viatris plans a phase-I bioavailability trial (In volunteers) in Netherlands(PO), (CTIS2025-522320-27-00)

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