PRX 106

Drug Profile

PRX 106

Alternative Names: Anti-TNF therapeutic - Protalix Biotherapeutics; Anti-tumour necrosis factor therapeutic - Protalix Biotherapeutics; OPRX 106; pr-anti-TNF; PRX-106

Latest Information Update: 10 Jul 2018

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At a glance

  • Originator Protalix Biotherapeutics
  • Developer Protalix BioTherapeutics
  • Class Recombinant fusion proteins
  • Mechanism of Action Interferon gamma inhibitors; Interleukin 10 stimulants; Regulatory T-lymphocyte stimulants; Tumour necrosis factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Inflammatory bowel diseases

Highest Development Phases

  • Phase II Ulcerative colitis
  • Preclinical Inflammatory bowel diseases; Non-alcoholic steatohepatitis
  • No development reported Autoimmune disorders; Crohn's disease; Fatty liver; Hepatitis; Rheumatoid arthritis

Most Recent Events

  • 05 Jun 2018 Safety and efficacy results from final analysis of phase II trial in Ulcerative colitis released by Protalix BioTherapeutics
  • 02 Jun 2018 Efficacy and Immunogenicity data from a phase IIa trial in Ulcerative Colitis presented at the Digestive Disease Week 2018 (DDW-2018)
  • 28 May 2018 No recent reports of development identified for preclinical development in Fatty liver in Israel (PO)
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