Taselisib - Genentech/Chugai Pharmaceutical

Drug Profile

Taselisib - Genentech/Chugai Pharmaceutical

Alternative Names: GDC 0032; RG-7604

Latest Information Update: 28 Jun 2018

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At a glance

  • Originator Genentech
  • Developer Chugai Pharmaceutical; Genentech; Netherlands Cancer Institute
  • Class 3-ring heterocyclic compounds; Amides; Antineoplastics; Benzazepines; Oxazepines; Pyrazoles; Small molecules; Triazoles
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Breast cancer
  • Phase II/III Non-small cell lung cancer
  • Phase I/II Growth disorders; Gynaecological cancer
  • Phase I Solid tumours

Most Recent Events

  • 01 Jun 2018 Efficacy and adverse events data from a phase III SANDPIPER trial in Breast cancer presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 04 May 2018 Phase I development in Solid tumours is ongoing (Chugai pipeline, May 2018)
  • 03 May 2018 Genentech and Vanderbilt-Ingram Cancer Center suspends patient enrolment due to interim analysis in a phase Ib/II trial in Breast cancer (Combination therapy, Late-stage disease, Second-line therapy or greater, Metastatic disease) in USA (PO) (NCT02457910)
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