Utomilumab - Pfizer

Drug Profile

Utomilumab - Pfizer

Alternative Names: PF-05082566; PF-2566; PF-5082566

Latest Information Update: 31 Jul 2018

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At a glance

  • Originator Pfizer
  • Developer Immatics US; Kyowa Hakko Kirin; M. D. Anderson Cancer Center; Pfizer
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CD137 antigen agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer; Oropharyngeal cancer; Solid tumours
  • Phase I Colorectal cancer; Ovarian cancer
  • No development reported B cell lymphoma; Non-Hodgkin's lymphoma

Most Recent Events

  • 16 Jul 2018 Phase-I clinical trials in Ovarian cancer (Combination therapy, Recurrent, Second-line therapy or greater, Late-stage disease) in USA (IV) (NCT03318900)
  • 21 Jun 2018 Phase-II clinical trials in Breast cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT03414658)
  • 24 Apr 2018 Pfizer and Kyowa Hakko Kirin terminate phase I trial in Solid tumours in USA (NCT02444793)
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