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PCS 499

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Drug Profile

PCS 499

Alternative Names: CTP-499; PCS-499

Latest Information Update: 17 Apr 2024

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At a glance

  • Originator Concert Pharmaceuticals
  • Class Anti-inflammatories; Antifibrotics; Organic deuterium compounds; Skin disorder therapies; Small molecules
  • Mechanism of Action Antioxidants; Phosphoric diester hydrolase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Necrobiosis lipoidica
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Necrobiosis lipoidica
  • Discontinued Diabetic nephropathies; Kidney disorders

Most Recent Events

  • 16 Apr 2024 PCS 499 is available for licensing as of 16 Apr 2024
  • 03 Aug 2023 Processa Pharmaceuticals terminates a phase II trial in Necrobiosis lipoidica (In adults, In the elderly) in the US (PO, Tablet) due to lack of enrollment of this ultra rare disease (NCT04800562)
  • 06 Mar 2023 Concert Pharmaceuticals has been acquired by Sun Pharmaceutical Industries

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