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Foscenvivint - PRISM Pharma Co

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Drug Profile

Foscenvivint - PRISM Pharma Co

Alternative Names: CBP-beta catenin inhibitor; ICG-001; OP-724; PRI-724

Latest Information Update: 24 Nov 2023

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At a glance

  • Originator PRISM BioLab; University of Southern California
  • Developer Ohara Pharmaceutical; PRISM Pharma Co; Syneos Health; Tokyo Metropolitan Komagome Hospital
  • Class Antifibrotics; Antineoplastics; Pyrazines; Quinolines; Small molecules; Triazines
  • Mechanism of Action Beta catenin inhibitors; CREB-binding protein inhibitors; Wnt signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Liver cirrhosis
  • Phase I Primary biliary cirrhosis
  • Preclinical Hepatic fibrosis; Prostate cancer
  • Discontinued Acute myeloid leukaemia; Chronic myeloid leukaemia; Pancreatic cancer; Solid tumours

Most Recent Events

  • 14 Nov 2023 Phase-II clinical trials in Liver cirrhosis in Japan (IV) (NCT06144086)
  • 03 Jan 2023 Phase I developement for Primary biliary cirrhosis is ongoing in Japan (IV) (Ohara Pharmaceutical pipeline, January 2023)
  • 04 Nov 2022 Preclinical trials in Hepatic fibrosis in Japan (Intraperitoneal), prior to November 2022

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