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Foscenvivint - PRISM Pharma Co

Drug Profile

Foscenvivint - PRISM Pharma Co

Alternative Names: CBP-beta catenin inhibitor; ICG-001; OP-724; PRI-724

Latest Information Update: 30 May 2022

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At a glance

  • Originator PRISM BioLab; University of Southern California
  • Developer Ohara Pharmaceutical; PRISM Pharma Co; Syneos Health; Tokyo Metropolitan Komagome Hospital
  • Class Antifibrotics; Antineoplastics; Pyrazines; Quinolines; Small molecules; Triazines
  • Mechanism of Action Beta catenin inhibitors; CREB-binding protein inhibitors; Wnt signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Liver cirrhosis
  • Phase I Primary biliary cirrhosis
  • Preclinical Prostate cancer
  • Discontinued Acute myeloid leukaemia; Chronic myeloid leukaemia; Hepatic fibrosis; Pancreatic cancer; Solid tumours

Most Recent Events

  • 08 Apr 2022 Preclinical trials in Prostate cancer in Japan (unspecified route)
  • 08 Apr 2022 Pharmacodynamics data from a preclinical in prostate cancer presented at the 113th Annual Meeting of the American Association for Cancer Research (AACR-2022)
  • 31 Mar 2022 OHARA Pharmaceuticals completes phase I trial in Primary biliary cirrhosis in Japan (IV) (NCT04047160)
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