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Vilobelimab - InflaRx

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Drug Profile

Vilobelimab - InflaRx

Alternative Names: CaC-P29; Gohibic; IFX-1; Vilobelimab-InflaRx

Latest Information Update: 21 Mar 2025

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At a glance

  • Originator InflaRx
  • Class Anti-infectives; Anti-inflammatories; Antineoplastics; Antivirals; Monoclonal antibodies; Skin disorder therapies; Vascular disorder therapies
  • Mechanism of Action Complement C5a inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pyoderma gangrenosum
  • New Molecular Entity Yes
  • Available For Licensing Yes - Adult respiratory distress syndrome

Highest Development Phases

  • Registered COVID-19 pneumonia
  • Phase III Pyoderma gangrenosum
  • Phase II Adult respiratory distress syndrome; Hidradenitis suppurativa
  • Suspended Granulomatosis with polyangiitis; Microscopic polyangiitis
  • No development reported Inflammation
  • Discontinued Sepsis; Squamous cell cancer; Systemic inflammatory response syndrome

Most Recent Events

  • 13 Feb 2025 InflaRx initiates phase-II trial for Adult respiratory distress syndrome in USA (IV) (NCT06701682)
  • 13 Feb 2025 Phase-II clinical trials in Adult respiratory distress syndrome in USA (IV) (NCT06703073)
  • 15 Jan 2025 Registered for COVID-19 pneumonia in European Union (IV)

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