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CLR 1404 I-124

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Drug Profile

CLR 1404 I-124

Alternative Names: 124I-CLR1404; CLR-124; CLR1404 I-124; I-124-CLR1404; I124-NM404; LIGHT

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator University of Michigan Medical School
  • Developer Cellectar Biosciences; University of Wisconsin-Madison
  • Class Drug conjugates; Imaging agents; Iodine radioisotopes; Phospholipid ethers; Radiopharmaceutical diagnostics; Small molecules
  • Mechanism of Action Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Glioblastoma
  • Phase I/II Brain cancer; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 09 Mar 2021 Cellectar Biosciences has patent protection for Phospholipid-ether analogues in Japan
  • 12 Jun 2020 Cellectar Biosciences has patent pending for composition of matter and use of phospholipid-ether analogs in Europe
  • 20 Aug 2019 CLR 1404 I-124 is still in clinical trials for Cancer in USA (Cellectar Biosciences 10K 2018)

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