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Osugacestat - Ayala Pharmaceuticals

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Drug Profile

Osugacestat - Ayala Pharmaceuticals

Alternative Names: AL-101; BM-0018; BMS-906024

Latest Information Update: 28 Oct 2024

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Ayala Pharmaceuticals; Bristol-Myers Squibb; M. D. Anderson Cancer Center
  • Class Amides; Antineoplastics; Benzene derivatives; Benzodiazepines; Fluorinated hydrocarbons; Small molecules
  • Mechanism of Action Amyloid precursor protein secretase inhibitors; Notch receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Adenoid cystic carcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adenoid cystic carcinoma; Triple negative breast cancer
  • No development reported Fibroma; Precursor T-cell lymphoblastic leukaemia-lymphoma; Solid tumours; T-cell lymphoma

Most Recent Events

  • 28 Oct 2024 No recent reports of development identified for clinical-Phase-Unknown development in Fibroma in Unknown (IV)
  • 28 Oct 2024 No recent reports of development identified for phase-I development in Adenoid-cystic-carcinoma(Late-stage disease, Metastatic disease, Neoadjuvant therapy) in USA (IV)
  • 26 Mar 2024 Immunome acquires osugacestat from Ayala Pharmaceuticals

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