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Acumapimod - Mereo BioPharma

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Drug Profile

Acumapimod - Mereo BioPharma

Alternative Names: Acumapimod; BCT-197; BCT197A2201

Latest Information Update: 17 Oct 2025

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At a glance

  • Originator Novartis
  • Developer Mereo BioPharma; Novartis
  • Class Anti-inflammatories; Antibronchitics; Benzamides; Cyclopropanes; Pyrazoles; Small molecules
  • Mechanism of Action P38 mitogen-activated protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Chronic obstructive pulmonary disease
  • Discontinued Acute kidney injury

Most Recent Events

  • 17 May 2025 Updated efficacy data from the phase II AETHER trial for Chronic obstructive pulmonary disease presented at the 121st International Conference of the American Thoracic Society (ATS-2025)
  • 04 Aug 2023 Chemical structure information added
  • 31 Dec 2022 Mereo Biopharma has patent protection for acumapimod in USA and other undisclosed locations

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