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Ifebemtinib - InxMed

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Drug Profile

Ifebemtinib - InxMed

Alternative Names: BI 853520; ifebe; IN-10018

Latest Information Update: 04 Mar 2026

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At a glance

  • Originator Boehringer Ingelheim
  • Developer Boehringer Ingelheim; InxMed
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Focal adhesion protein tyrosine kinase inhibitors; PTK2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Non-small cell lung cancer
  • Phase I/II Breast cancer; Head and neck cancer; Malignant melanoma; Ovarian cancer; Pancreatic cancer; Small cell lung cancer; Solid tumours
  • No development reported Uveal melanoma

Most Recent Events

  • 28 Feb 2026 InxMed initiates a phase Ib/II trial for Solid tumours (Combination therapy, Late-stage disease, Second-line therapy or greater, Metastatic disease) in China (PO) (NCT07441174)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in Uveal-melanoma(Combination therapy, Metastatic disease) in USA (PO)
  • 28 Feb 2026 No recent reports of development identified for phase-I development in Uveal-melanoma(Metastatic disease, Monotherapy) in USA (PO)

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