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Ifebemtinib - InxMed

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Drug Profile

Ifebemtinib - InxMed

Alternative Names: BI 853520; ifebe; IN-10018

Latest Information Update: 18 Aug 2026

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At a glance

  • Originator Boehringer Ingelheim
  • Developer Boehringer Ingelheim; InxMed; Wuhan Union Hospital
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Focal adhesion protein tyrosine kinase inhibitors; PTK2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Non-small cell lung cancer
  • Phase II Adenocarcinoma; Colorectal cancer
  • Phase I/II Breast cancer; Head and neck cancer; Malignant melanoma; Ovarian cancer; Pancreatic cancer; Small cell lung cancer; Solid tumours
  • No development reported Uveal melanoma

Most Recent Events

  • 18 Aug 2026 Phase-II clinical trials in Colorectal cancer (Combination therapy) in China (PO) prior o August 2026 ((InxMed pipeline, August 2026)
  • 17 Jun 2026 Capital Medical University plans a phase Ib trial for Meningioma (Combination therapy, Recurrent) in China (PO), in June 2026 , (NCT07652762)
  • 02 Jun 2026 Efficacy and adverse events data from a phase Ib/II trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)

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