Drug Profile
Polatuzumab vedotin - Genentech
Alternative Names: ADC DCDS4501A; anti-CD79b-VC-MMAE; Antibody-Drug Conjugate DCDS4501A; DCDS-4501A; FCU-2711; polatuzumab vedotin-piic; polatuzumab vedotin-piiq; Polivy; RG-7596; RO-5541077; RO-5541077-000Latest Information Update: 15 Dec 2023
Price :
$50
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At a glance
- Originator Genentech
- Developer Chugai Pharmaceutical; Genentech; Roche; Weill Cornell Medical College
- Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
- Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Diffuse large B cell lymphoma
- Phase III Follicular lymphoma
- Phase II Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma; Richter's syndrome
Most Recent Events
- 14 Dec 2023 Seagen has been acquired by Pfizer
- 09 Dec 2023 Efficacy data from a phase III POLARIX trial in Diffuse large B cell lymphoma presented at the 65th American Society of Hematology Annual Meeting (ASH-Hem-2023)
- 09 Dec 2023 Efficacy and adverse event data from a phase I trial in Diffuse large B cell lymphoma presented at the 65th American Society of Hematology Annual Meeting and Exposition 2023 (ASH-Hem-2023)