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BOLD 100

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Drug Profile

BOLD 100

Alternative Names: BOLD 100; IT-139; KP 1339; NKP-1339

Latest Information Update: 28 Aug 2024

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At a glance

  • Originator Medical University of Vienna; Queens University Belfast; University of Vienna
  • Developer Bold Therapeutics; Georgetown University; Hana Pharm; Intezyne; University of Ottawa
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Apoptosis stimulants; DNA inhibitors; Molecular chaperone GRP78 protein inhibitors; Reactive oxygen species stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer; Pancreatic cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Biliary cancer; Cholangiocarcinoma; Colorectal cancer; Gastric cancer; Pancreatic cancer
  • Preclinical Triple negative breast cancer
  • No development reported COVID 2019 infections; Solid tumours

Most Recent Events

  • 28 Aug 2024 No recent reports of development identified for preclinical development in COVID-2019-infections in Canada (IV)
  • 03 Jun 2024 Efficacy and adverse events data from a phase Ib/IIa trial in Biliary cancer and Gastric cancer released by Bold Therapeutics
  • 03 Jun 2024 Bold Therapeutics plans a phase II randomised trial for Colorectal cancer (Second-line therapy or greater, Combination therapy) in multiple countries (IV)

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