Drug Profile

Tigulixostat - LG Chem

Alternative Names: IBI-128; IBI-350; LC-350189; LR-19074

Latest Information Update: 18 Sep 2025

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At a glance

Originator LG Life Sciences
Developer Innovent Biologics; LG Chem
Class Antigouts; Carboxylic acids; Indoles; Nitriles; Pyrazoles; Small molecules
Mechanism of Action Xanthine oxidase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase III Gout

Most Recent Events

07 Sep 2025 Efficacy and adverse events data from a phase II trial in Gout released by Innovent Biologics
07 Sep 2025 Innovent Biologics plans a phase III trial for Gout in China (PO), in the second half of 2025
06 May 2025 LG Chem completes a Phase-III clinical trials in Gout in USA (PO) (NCT05586971)

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