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Topiroxostat - Fuji Yakuhin/Sanwa Kagaku Kenkyusho

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Drug Profile

Topiroxostat - Fuji Yakuhin/Sanwa Kagaku Kenkyusho

Alternative Names: FYX-051; SK-0910; Topiroric; Uriadec

Latest Information Update: 30 Dec 2022

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At a glance

  • Originator Fuji Yakuhin
  • Developer Fuji Yakuhin; Sanwa Kagaku Kenkyusho
  • Class Nitriles; Pyridines; Small molecules; Triazoles
  • Mechanism of Action Xanthine dehydrogenase inhibitors; Xanthine oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Gout; Hyperuricaemia
  • No development reported Diabetic nephropathies
  • Discontinued Heart failure

Most Recent Events

  • 30 Dec 2022 Discontinued - Clinical-Phase-Unknown for Heart failure in Japan (PO)
  • 28 Feb 2020 No recent reports of development identified for clinical-Phase-Unknown development in Heart-failure in Japan (PO, Tablet)
  • 04 Mar 2019 Sanwa Kagaku Kenkyusho and Nippon Medical School Hospital completes the SOUGHT clinical trial for Hyperuricaemia (In patients with Congestive heart failure) in Japan (UMIN000024981)

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