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Decoglurant

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Drug Profile

Decoglurant

Alternative Names: mGluR2/3 antagonist - Roche; R-1578; RG-1578; RO-4995819; RO4995819/F05

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Roche
  • Class Amines; Antidementias; Antidepressants; Pyrazoles; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action Metabotropic glutamate receptor 2 antagonists; Metabotropic glutamate receptor 3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Dementia; Major depressive disorder

Most Recent Events

  • 28 Jan 2015 Discontinued - Phase-I for Major depressive disorder (Combination therapy, In volunteers) in France (PO)
  • 28 Jan 2015 Discontinued - Phase-I for Major depressive disorder (In volunteers) in France (PO)
  • 28 Jan 2015 Discontinued - Phase-II for Major depressive disorder (Adjunctive treatment) in Austria (PO)

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