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IMC CS4

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Drug Profile

IMC CS4

Alternative Names: Anti-CSF-1R-monoclonal-antibody-ImClone; IMCCS4; LY-3022855

Latest Information Update: 30 Jun 2023

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At a glance

  • Originator ImClone Systems
  • Developer AstraZeneca; Dana-Farber Cancer Institute; Eli Lilly and Company; Merck Sharp & Dohme; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Macrophage colony-stimulating factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Malignant melanoma; Pancreatic cancer; Prostate cancer; Solid tumours

Most Recent Events

  • 29 May 2023 Discontinued - Phase-I for Breast cancer (Late-stage disease, Second-line therapy or greater) in USA (IV)
  • 29 May 2023 Discontinued - Phase-I for Pancreatic cancer (Combination therapy, Second-line therapy or greater) in USA (IV)
  • 29 May 2023 Discontinued - Phase-I for Prostate cancer (Late-stage disease, Second-line therapy or greater) in USA (IV)

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