Research programme: glucose metabolism therapeutics - XOMA

Drug Profile

Research programme: glucose metabolism therapeutics - XOMA

Alternative Names: Insulin receptor-regulating antibodies - XOMA; X 129; XMet program; XMetA; XMetD; XMetD antibody fragment (Fab); XMetS; XOMA-129

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator XOMA
  • Class Antihypoglycaemics; Monoclonal antibodies
  • Mechanism of Action Insulin receptor agonists; Insulin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Type 1 diabetes mellitus; Type 2 diabetes mellitus

Highest Development Phases

  • Preclinical Hypoglycaemia
  • No development reported Diabetes mellitus

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Diabetes-mellitus in USA (Parenteral)
  • 01 Apr 2017 Pharmacodynamics data from preclinical studies in Hypoglycaemia presented at the 99th Annual Meeting of the Endocrine Society (ENDO-2017)
  • 04 Apr 2016 Pharmacodynamics data from a preclinical trial in Diabetes mellitus released by XOMA
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