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Hydromethylthionine mesylate - TauRx Pharmaceuticals

Drug Profile

Hydromethylthionine mesylate - TauRx Pharmaceuticals

Alternative Names: HMTM; Hydromethylthionine; leuco-methylthioninium; Leuco-methylthioninium-bis(hydromethanesulfonate); LMT-X; LMTM; LMTX; TRx-0237

Latest Information Update: 18 Jul 2023

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At a glance

  • Originator TauRx Pharmaceuticals
  • Class Antidementias; Diamines; Mesylates; Phenothiazines; Small molecules
  • Mechanism of Action Synuclein inhibitors; Tau protein inhibitors; TDP-43 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Dementia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Alzheimer's disease; Dementia
  • No development reported Parkinson's disease
  • Discontinued Progressive supranuclear palsy

Most Recent Events

  • 16 Jul 2023 Pharmacodynamics data from a phase III LUCIDITY trial in Alzheimer’s disease released by TauRx pharmaceuticals
  • 04 Apr 2023 TauRx Pharmaceuticals completes the phase III LUCIDITY trial (Monotherapy) for Alzheimer's disease in USA, Belgium, Spain, Canada, France, Italy, Poland and United Kingdom (PO) (NCT03446001)
  • 30 Nov 2022 Updated adverse events and efficacy data from the phase III LUCIDITY in Alzheimer's disease released by TauRx Pharmaceuticals
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