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Hydromethylthionine mesylate - TauRx Pharmaceuticals

Drug Profile

Hydromethylthionine mesylate - TauRx Pharmaceuticals

Alternative Names: HMTM; Hydromethylthionine; leuco-methylthioninium; Leuco-methylthioninium-bis(hydromethanesulfonate); LMT-X; LMTM; LMTX; TRx-0237

Latest Information Update: 08 Feb 2024

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At a glance

  • Originator TauRx Pharmaceuticals
  • Class Antidementias; Diamines; Mesylates; Phenothiazines; Small molecules
  • Mechanism of Action Synuclein inhibitors; Tau protein inhibitors; TDP-43 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Dementia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Alzheimer's disease; Dementia
  • No development reported Parkinson's disease
  • Discontinued Progressive supranuclear palsy

Most Recent Events

  • 06 Feb 2024 TauRx Pharmaceuticals initiates regulatory engagement in the UK and the US for hydromethylthionine mesylate approval
  • 06 Feb 2024 TauRx Pharmaceuticals plans to launch hydromethylthionine mesylate for Alzheimer’s disease
  • 16 Jul 2023 Pharmacodynamics data from a phase III LUCIDITY trial in Alzheimer’s disease released by TauRx pharmaceuticals
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