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Cobicistat/darunavir - Janssen R&D Ireland

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Drug Profile

Cobicistat/darunavir - Janssen R&D Ireland

Alternative Names: Darunavir/cobicistat; DRV/COBI; G 006; JNJ-48763364/TMC114; Prezcobix; Rezolsta; TMC114/ JNJ-48763364

Latest Information Update: 20 Oct 2022

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At a glance

  • Originator Gilead Sciences; Tibotec Pharmaceuticals
  • Developer Gilead Sciences; Janssen R&D Ireland; Janssen Research & Development
  • Class Antiretrovirals; Carbamates; Deoxyribonucleosides; Morpholines; Purines; Pyrimidine nucleosides; Small molecules; Sulfonamides; Thiazoles
  • Mechanism of Action Cytochrome P-450 enzyme system inhibitors; HIV protease inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - HIV-1 infections
  • New Molecular Entity No

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 28 Sep 2022 Janssen completes a phase I bioequivalence study in Healthy volunteers in Belgium (PO) (EudraCT2021-003955-40)
  • 23 Sep 2022 Janssen Research & Development completes a phase I trial in HIV-1 infections (In adolescents, In the elderly, In children, In adults) in South Africa, Spain and USA (PO) (NCT05197075)
  • 19 Aug 2022 Phase-I clinical trials in HIV-1 infections (In adolescents, In adults, In children, In the elderly) in Spain (PO) (NCT05197075)

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