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Fruquintinib - HUTCHMED

Drug Profile

Fruquintinib - HUTCHMED

Alternative Names: Aiyoute; Elunate; FRUZAQLA; HMPL-013; TAK-113

Latest Information Update: 08 Mar 2024

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At a glance

  • Originator Hutchison MediPharma
  • Developer BeiGene; Eli Lilly and Company; Genor Biopharma; Hutchison MediPharma; HUTCHMED; Shanghai Junshi Biosciences
  • Class Antineoplastics; Benzofurans; Quinazolines; Small molecules
  • Mechanism of Action Vascular endothelial growth factor receptor 3 antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Colorectal cancer
  • Preregistration Gastric cancer
  • Phase III Non-small cell lung cancer
  • Phase II/III Renal cell carcinoma
  • Phase II Solid tumours
  • Phase I/II Endometrial cancer; Triple negative breast cancer

Most Recent Events

  • 28 Feb 2024 HUTCHMED announces intention to complete EMA MAA review for Colorectal cancer (Second-line therapy or greater, Metastatic disease) in mid-2024
  • 28 Feb 2024 HUTCHMED announces intention to registration filing to the NMPA for Endometrial cancer (second-line Therapy or greater) in early 2024
  • 28 Feb 2024 HUTCHMED expects PMDA to complete NDA review for Colorectal cancer (Second-line therapy or greater, Metastatic disease) in late-2024
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