Abemaciclib - Eli Lilly

Drug Profile

Abemaciclib - Eli Lilly

Alternative Names: Abemaciclib mesylate; Bemaciclib; Bemaciclib mesylate; LY-2835219; Verzenio

Latest Information Update: 07 Mar 2018

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At a glance

  • Originator Eli Lilly
  • Developer Dana-Farber Cancer Institute; Eli Lilly; Memorial Sloan-Kettering Cancer Center; Merck Sharp & Dohme
  • Class Aminopyridines; Antineoplastics; Benzimidazoles; Piperazines; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer
  • Phase III Non-small cell lung cancer
  • Phase II Brain cancer; Glioblastoma; Liposarcoma; Mantle-cell lymphoma; Pancreatic cancer; Solid tumours
  • Phase I Cancer

Most Recent Events

  • 28 Feb 2018 No recent reports of development identified for phase-I development in Cancer(In volunteers) in United Kingdom (IV, Infusion)
  • 27 Feb 2018 Launched for Breast cancer (Combination therapy, First-line therapy, Late-stage disease) in USA (PO)
  • 26 Feb 2018 Registered for Breast cancer (Combination therapy, First-line therapy, Late-stage disease) in Puerto Rico (PO)
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