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MS 553

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Drug Profile

MS 553

Alternative Names: MS-553

Latest Information Update: 26 May 2025

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At a glance

  • Originator Pfizer
  • Developer Jiangsu MingSight-Relin Pharmaceutical; MingSight Pharmaceuticals
  • Class Antineoplastics; Eye disorder therapies
  • Mechanism of Action Protein kinase C beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma
  • No development reported Diabetic macular oedema; Diabetic retinopathy

Most Recent Events

  • 18 May 2025 MingSight Pharmaceuticals plans a phase Ib/II trial for Chronic Lymphocytic Leukemia (Second-line therapy or greater) (PO) in July 2025 (NCT06979076)
  • 02 Apr 2025 MingSight Pharmaceuticals reinitiates phase-I clinical trials in Diabetic macular oedema in China (PO) (NCT04187443)
  • 18 Jul 2024 MingSight Pharmaceuticals suspends a phase-I clinical trials in Diabetic macular oedema in China (PO) due to major protocol revisions (NCT04187443)

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