Famitinib - Jiangsu Hengrui Medicine
Alternative Names: Famitinib maleate; SHR 1020Latest Information Update: 06 Jun 2025
At a glance
- Originator Jiangsu Hengrui Medicine Co.
- Class Antineoplastics; Diethylamines; Fluorobenzenes; Indoles; Pyrroles; Small molecules
- Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Platelet-derived growth factor receptor antagonists; Proto-oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Registered Cervical cancer
- Phase III Colorectal cancer; Gastrointestinal stromal tumours; HER2 negative breast cancer; Non-small cell lung cancer; Triple negative breast cancer
- Phase II Biliary cancer; Endometrial cancer; Fallopian tube cancer; Nasopharyngeal cancer; Neuroendocrine tumours; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Renal cell carcinoma; Solid tumours; Thyroid cancer; Urogenital cancer
- Phase I/II Osteosarcoma
- No development reported Fibroma
Most Recent Events
- 29 May 2025 Registered for Cervical cancer (Second-line therapy or greater, Recurrent, Metastatic disease, Combination therapy) in China (PO, Capsule) - First Global Approval
- 08 Apr 2025 Phase-III clinical trials in HER2-negative-breast-cancer (Combination therapy, Neoadjuvant therapy, First-line therapy) in China (PO) (NCT06913777)
- 28 Dec 2024 No recent reports of development identified for clinical-Phase-Unknown development in Fibroma in China (PO)