Famitinib

Drug Profile

Famitinib

Alternative Names: Famitinib maleate; SHR 1020

Latest Information Update: 09 Mar 2017

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Class Antineoplastics; Diethylamines; Fluorobenzenes; Indoles; Pyrroles; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Platelet-derived growth factor receptor antagonists; Proto oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor 3 antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Colorectal cancer; Non-small cell lung cancer
  • Phase II Gastrointestinal stromal tumours; Neuroendocrine tumours; Renal cell carcinoma
  • No development reported Breast cancer; Nasopharyngeal cancer

Most Recent Events

  • 01 Feb 2017 Jiangsu Hengrui Medicine terminates a phase III trial in Non-small cell lung cancer (Late-stage disease, Second-line therapy or greater, Metastatic disease, Recurrent, Combination therapy) due to difficulty in recruitment in China (PO) (NCT02766140)
  • 06 May 2016 Jiangsu Hengrui Medicine plans a phase III trial for Non-small cell lung cancer (Combination therapy, Late-stage disease, Recurrent, Metastatic disease; Second-line therapy or greater) in China (NCT02766140)
  • 01 May 2016 Phase-III clinical trials in Non-small cell lung cancer (Late-stage disease, Second-line therapy or greater, Metastatic disease, Recurrent, Combination therapy) in China (PO)
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