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Famitinib - Jiangsu Hengrui Medicine

Drug Profile

Famitinib - Jiangsu Hengrui Medicine

Alternative Names: Famitinib maleate; SHR 1020

Latest Information Update: 19 Feb 2024

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Fudan University; Jiangsu Hengrui Medicine Co.
  • Class Antineoplastics; Diethylamines; Fluorobenzenes; Indoles; Pyrroles; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Platelet-derived growth factor receptor antagonists; Proto oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor 3 antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Cervical cancer; Colorectal cancer; Gastrointestinal stromal tumours; Non-small cell lung cancer
  • Phase II Biliary cancer; Endometrial cancer; Fallopian tube cancer; HER2 negative breast cancer; Nasopharyngeal cancer; Neuroendocrine tumours; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Renal cell carcinoma; Solid tumours; Thyroid cancer; Triple negative breast cancer; Urogenital cancer
  • Phase I/II Osteosarcoma
  • Clinical Phase Unknown Fibroma
  • No development reported Breast cancer

Most Recent Events

  • 09 Feb 2024 Jiangsu HengRui Medicine terminates phase III trial in Gastrointestinal stromal tumours (Inoperable/Unresectable, Late-stage disease) in China (PO) due to R&D business strategy (NCT04409223)
  • 05 Dec 2023 Efficacy and adverse events data from a phase I/II trial in HER2-negative breast cancer presented at the 46th Annual San Antonio Breast Cancer Symposium (SABCS-2023)
  • 28 Nov 2023 Ruijin Hospital plans a phase II trial for famitinib in Thyroid cancer (Late-stage disease, Inoperable/Unresectable, Metastatic disease, Combination therapy) (PO) in December 2023 (NCT06146985)
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