Dextran sulfate-low molecular weight - TikoMed

Drug Profile

Dextran sulfate-low molecular weight - TikoMed

Alternative Names: Dextran sulfate sodium; DSSS5; IBsolvMIR; Low molecular weight dextran sulfate; TM-400

Latest Information Update: 22 May 2018

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At a glance

  • Originator TikoMed
  • Developer TikoMed; Uppsala University
  • Class Anticoagulants; Antihyperlipidaemics; Glucans; Small molecules
  • Mechanism of Action Blood coagulation factor inhibitors; Complement system protein inhibitors; Immunosuppressants; Intracellular signalling peptide and protein stimulants; Stem cell modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Stem cell mobilisation; Pancreas transplant rejection
  • New Molecular Entity No
  • Available For Licensing Yes - Pancreas transplant rejection

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Pancreas transplant rejection
  • Phase I Haematological malignancies

Most Recent Events

  • 15 May 2018 Phase-II clinical trials in Amyotrophic lateral sclerosis in Sweden (SC) (EudraCT2017-005065-47)
  • 26 Sep 2016 Phase-II development for Pancreas transplant rejection is ongoing in Sweden
  • 21 Aug 2014 Tikomed completes a phase II trial in Pancreas transplant rejection (Combination therapy) in Sweden (EudraCT2008-001210-25 )
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