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DLX 105

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Drug Profile

DLX 105

Alternative Names: DLX-105; ESBA-105; Humanised single-chain (scFv) antibody directed against human TNF-alpha

Latest Information Update: 11 May 2021

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At a glance

  • Originator ESBATech
  • Developer Delenex Therapeutics; ESBATech; Kuur Therapeutics
  • Class Anti-inflammatories; Eye disorder therapies; Immunoglobulin fragments
  • Mechanism of Action Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Age-related macular degeneration; Behcet's syndrome; Crohn's disease; Dry eyes; Hidradenitis suppurativa; Ocular inflammation; Osteoarthritis; Plaque psoriasis; Uveitis

Most Recent Events

  • 04 May 2021 Kuur Therapeutics has been acquired by Athenex
  • 13 Mar 2020 Cell Medica is now called Kuur Therapeutics
  • 09 Apr 2019 Novartis completed the spin-off of Alcon

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