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Avadomide - Celgene Corporation

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Drug Profile

Avadomide - Celgene Corporation

Alternative Names: CC 122

Latest Information Update: 28 May 2025

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At a glance

  • Originator Celgene Corporation
  • Developer Bristol-Myers Squibb; Celgene Corporation; H. Lee Moffitt Cancer Center and Research Institute; Juno Therapeutics
  • Class Antineoplastics; Piperidones; Quinazolines
  • Mechanism of Action CRBN protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Malignant melanoma
  • Phase I/II Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Liver cancer; Non-Hodgkin's lymphoma
  • No development reported Glioblastoma; Multiple myeloma; Solid tumours

Most Recent Events

  • 28 May 2025 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma(Combination therapy, Second-line therapy or greater) in France (PO, Capsule)
  • 28 May 2025 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma(Combination therapy, Second-line therapy or greater) in Italy (PO, Capsule)
  • 28 May 2025 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma(Combination therapy, Second-line therapy or greater) in Netherlands (PO, Capsule)

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