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Ciforadenant - Corvus Pharmaceuticals

Drug Profile

Ciforadenant - Corvus Pharmaceuticals

Alternative Names: CPI-444; V 81444

Latest Information Update: 05 Jan 2024

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At a glance

  • Originator Vernalis
  • Developer Corvus Pharmaceuticals; Genentech; M. D. Anderson Cancer Center; Vernalis
  • Class Amines; Antineoplastics; Antiparkinsonians; Behavioural disorder therapies; Furans; Pyridines; Pyrimidines; Small molecules; Triazoles
  • Mechanism of Action Adenosine A2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Renal cell carcinoma
  • Phase I/II Non-small cell lung cancer
  • Phase I Multiple myeloma; Solid tumours
  • No development reported Attention-deficit hyperactivity disorder; Cancer; Parkinson's disease

Most Recent Events

  • 05 Jan 2024 Ciforadenant is still in phase I trials for Solid tumours in Australia and the USA (NCT03454451)
  • 04 Jul 2023 Phase-II clinical trials in Renal cell carcinoma (First-line therapy) (PO) before July 2023 (Corvus Pharmceuticals pipeline, July 2023)
  • 19 Feb 2023 Corvus Pharmaceuticals comletes a phase I/Ib trial for Cancer (Second-line therapy or greater, Late-stage disease, Combination therapy) in USA and Australia (PO) (NCT03454451)
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