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Labetuzumab govitecan - Immunomedics

Drug Profile

Labetuzumab govitecan - Immunomedics

Alternative Names: Anti-carcinoembryonic antigen monoclonal antibody; Anti-CEA monoclonal antibody; anti-CEACAM5-SN-38; GS-0130; hMN-14-SN38; hMN-14-SN38 antibody-drug conjugate; IMMU-0130; IMMU-130; Labetuzumab-SN38 conjugate; SN38-labetuzumab conjugate

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator IBC Pharmaceuticals; Immunomedics
  • Developer Immunomedics
  • Class Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Indolizines; Monoclonal antibodies; Pyrans; Pyrrolidines; Quinolines; Triazoles
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Colorectal cancer

Most Recent Events

  • 03 Dec 2020 Immunomedics withdraws enrolment in a phase II trial prior to enrollment for Colorectal cancer (Metastatic disease, Second-line therapy or greater, Late-stage disease) in USA (NCT01915472)
  • 23 Oct 2020 Immunomedics has been acquired by Gilead Sciences
  • 30 Jul 2018 Immunomedics signs a research collaboration agreement with Fred Hutchinson Cancer Research Center for evaluation of labetuzumab govitecan in the treatment of Prostate cancer (Combination therapy)
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