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Anetumab ravtansine - Bayer HealthCare

Drug Profile

Anetumab ravtansine - Bayer HealthCare

Alternative Names: Anti-mesothelin antibody-drug conjugate BAY 94-9343; Anti-mesothelin-ADC-BAY-94-9343; BAY-94-9343; BAY-94-9343-SPDB-DM4

Latest Information Update: 14 Feb 2024

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At a glance

  • Originator Bayer HealthCare
  • Developer Bayer HealthCare; ImmunoGen; MorphoSys; National Cancer Institute (USA)
  • Class Antineoplastics; Drug conjugates; Immunotoxins; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mesothelioma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Fallopian tube cancer; Lung cancer; Malignant thymoma; Mesothelioma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Solid tumours

Most Recent Events

  • 12 Feb 2024 ImmunoGen has been acquired by AbbVie
  • 04 Aug 2023 Discontinued - Phase-I for Fallopian tube cancer (Combination therapy, Late-stage disease, Metastatic disease, Recurrent) in Moldova, Belgium, USA, Spain (IV) (Bayer pipeline, August 2023)
  • 04 Aug 2023 Discontinued - Phase-I for Mesothelioma (Combination therapy, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in Italy (IV) (Bayer pipeline, August 2023)
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