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Research programme: mitochondrial disorders therapeutics - Mitopharm/Abliva

Drug Profile

Research programme: mitochondrial disorders therapeutics - Mitopharm/Abliva

Alternative Names: Ciclosporin derivatives - Abliva; mPT inhibitors; NICAM; NVP 016; NVP 017

Latest Information Update: 05 Jun 2020

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At a glance

  • Originator Mitopharm Limited; NeuroVive Pharmaceutical
  • Developer Abliva; Mitopharm Limited
  • Class Antineoplastics; Cardiovascular therapies; Ciclosporins; Obesity therapies
  • Mechanism of Action Cyclophilin D inhibitors; Mitochondrial permeability transition pore inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acute heart failure; Cancer; Obesity; Stroke

Most Recent Events

  • 28 May 2020 NeuroVive Pharmaceutical is now called Abliva
  • 21 Feb 2019 NeuroVive Pharmaceutical enters into an exclusive agreement with Oroboros Instruments to license and supply two of its first generation of succinate/malonate prodrugs originating from NVP 015 program
  • 04 Nov 2017 No recent reports of development identified for research development in Acute-heart-failure in Sweden (IV)

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