Research programme: mitochondrial disorders therapeutics - Mitopharm/NeuroVive

Drug Profile

Research programme: mitochondrial disorders therapeutics - Mitopharm/NeuroVive

Alternative Names: Ciclosporin derivatives - NeuroVive; mPT inhibitors; NICAM; NVP 015; NVP 015 programme; NVP 016; NVP 017; Succinate Prodrugs - NeuroVive/Lund; Succinic acid derivatives - Mitopharm/NeuroVive

Latest Information Update: 22 Jun 2018

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At a glance

  • Originator Mitopharm Limited; NeuroVive Pharmaceutical
  • Class Antineoplastics; Cardiovascular therapies; Ciclosporins; Obesity therapies; Succinates
  • Mechanism of Action Cyclophilin D inhibitors; Mitochondrial permeability transition pore inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Mitochondrial disorders
  • No development reported Acute heart failure; Cancer; Obesity; Stroke

Most Recent Events

  • 18 Jun 2018 NVP015 is still in preclinical trials for Mitochondrial disorders in Sweden
  • 28 Feb 2018 No recent reports of development identified for preclinical development in Mitochondrial disorders in Sweden (IV)
  • 04 Nov 2017 No recent reports of development identified for research development in Acute-heart-failure in Sweden (IV)
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