Drug Profile


Alternative Names: CPV; Cyclopropavir; MBX-400; NSC-D745998; ZSM-I-62

Latest Information Update: 11 Jun 2018

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At a glance

  • Originator Wayne State University School of Medicine
  • Developer Microbiotix
  • Class Antivirals; Cyclopropanes; Hypoxanthines; Purinones; Small molecules
  • Mechanism of Action DNA-directed DNA polymerase inhibitors; Ganciclovir-kinase-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cytomegalovirus infections

Most Recent Events

  • 11 Jun 2018 Filociclovir is still in phase I trials for Cytomegalovirus infections (In volunteers) in USA (PO, Capsule)
  • 07 Jun 2018 Microbiotix plans a phase II trial for Cytomegalovirus infections
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Cytomegalovirus infections(In volunteers) in USA (PO, Capsule)
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